The spleen is an organ located in
the upper left abdomen, and is roughly the size of a clenched fist. In the
adult, the spleen functions mainly as a blood filter, removing old red blood
cells. It also plays a role in both cell-mediated and humoral immune responses.
The spleen in located in the upper left quadrant of the
abdomen, under cover of the diaphragm and
the ribcage – and therefore cannot normally be palpated on clinical
examination (except when enlarged). It is an intraperitoneal organ, entirely
surrounded by peritoneum (except at the splenic hilum).
The spleen is connected to the stomach and kidney by
parts of the greater omentum – a double fold of peritoneum that originates from
the stomach:
The spleen has a slightly oval shape. It
is covered by a weak capsule that protects the organ whilst allowing it to
expand in size.
The outer surface of the spleen can be anatomically
divided into two:
·
Diaphragmatic surface – in contact with
diaphragm and ribcage.
·
Visceral surface – in contact with the other abdominal
viscera.
It has anterior, superior, posteromedial and inferior
borders. The posteromedial and inferior borders are smooth, whilst the anterior
and superior borders contain notches.
In enlargement of the spleen (known
as splenomegaly), the superior
border moves inferomedially, and its notches can be palpated.
The spleen is a highly vascular organ. It receives most of its
arterial supply from the splenic artery. This vessel arises from the celiac trunk, running
laterally along the superior aspect of the pancreas, within the splenorenal
ligament. As the artery reaches the spleen, it branches into five vessels –
each supplying a different part of the organ.
These arterial branches do not anastomose with each other –
giving rise to vascular segments of the spleen. This enables a surgeon to remove one of these
segments without affecting the others (a procedure known as a subtotal splenectomy).
Venous drainage occurs through the splenic
vein. It combines with the superior mesenteric vein to form
the hepatic portal vein.
The spleen is the abdominal organ
with the highest incidence of injury. A splenic rupture occurs when there is a
break in its fibroelastic capsule, disrupting the underlying parenchyma.
Rupture is caused by blunt or penetrating trauma. It is often
associated with left rib fractures, with a bony fragment easily tearing the
capsule.
As the spleen is a highly vascular
organ, its rupture results in profuse bleeding into the peritoneal cavity. Splenectomy is indicated where injury to the spleen and subsequent hemorrhage
are life threatening. This may be done as a sub-total (partial) splenectomy –
recall that there are no arterial anastomoses in the spleen – or as a total splenectomy.
The liver and bone marrow take over
some of the functions of the spleen, however, an individual who has no spleen
is more susceptible to some bacterial infections and as such, requires lifelong
antibiotics.
Comments
Post a Comment